Quercetin could affect both the in vivo and in vitro transport of a variety of commonly used drugs by modulating the uptake transporter organic anion transporter polypeptides (OATPs), organic anion transporters (OATs), efflux transporter P-glycoprotein (P-gp), multidrug resistance-related protein (MRP) and breast cancer resistance protein (BCRP), respectively. Quercetin can regulate various drug transporters, thereby affecting other drugs in vivo process.
YANG Ting-yu, LIU Ya-ni, SHI Shao-jun.
Advances in the Modulation of Quercetin on Drug Transporters[J]. Chinese Pharmaceutical Journal, 2017, 52(9): 721-725 https://doi.org/10.11669/cpj.2017.09.002
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